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To this aim, GSH and GSSG levels and activity of enzymes involved in GSH metabolism have been analyzed in both sensitive and resistant strains treated or not with the two antifungal drugs
doi: 10.1007/s00394-019-01931-8 149 MohrAEBasileAJMelisaSCSweazeaKLCarpenterKC
H.Jr.NybergS
Ionomycin significantly increased PS exposure in all conditions when compared to the DMSO control: Ringer (2.4% to 24%, p =0.0004), Ringer+Albumax (0.72% to 22%, p =0.0005), iRPMI (0.63% to 23%, p =0.0003) and iRPMI+Albumax (0.43% to 15%, p =0.0329)
Injectable Protocol (Systemic + Gut) For users who want systemic delivery alongside gut-targeted action: Loading Phase (Weeks 1 to 4): BPC-157: 250 to 500 mcg per day, subcutaneous injection (abdomen) KPV: 200 to 500 mcg per day, subcutaneous injection (abdomen) Maintenance Phase (Weeks 5 to 8): BPC-157: 250 mcg per day KPV: 200 to 300 mcg per day Extended Stack Options For enhanced regenerative effect beyond gut health, some practitioners add: TB-500: 2 to 2.5 mg twice weekly adds systemic cell migration and tissue remodeling for broader recovery GHK-Cu: 1 to 2 mg per day subcutaneous adds collagen production support and wound healing acceleration Timing and Administration Notes For oral gut-focused use, some users dose BPC-157 in the morning and KPV in the evening to maintain continuous coverage throughout the day
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